Michael Brecker had been suffering from the pre-leukemic disease MDS. He was diagnosed in 2005. In May 2006, he underwent an experimental stem cell operation that did not go as well as hoped. Doctor's had been searching for a suitable bone marrow match for Brecker over the past year but were unable to find the right match. Born in Philadelphia in 1949, Brecker recorded his own albums with his bands Horace Silver and the Brecker Brothers (with brother Randy). He was also a well-known session musican appearing on albums by Paul Simon, James Taylor and Yoko Ono.